|Dr. Joanna Holmes|
|Family||Peggy Holmes (mother in law)|
|Behind the scenes|
|Appearances||The Adventures of Shirley Holmes|
|Portrayed by||Elizabeth Shepherd|
Joanna Holmes is a doctor in virologist who disappeared for several years as a result of being in Rwanda during a civil war. She, Shirley, and Robert are reunited when Mr. Holmes is offered the chance to go to Rwanda on business. It is often said that Shirley shares her curiosity and determination to never give up.